NINE HISTORIC PARTNERS BUILT THE PROJECT:
Olivier Grovel and Catherine Roulier from ChiChaMVa team provide extracts from the collection of strains of marine fungi isolated from shellfish, sediments and seawater from regional shellfish growing areas. Currently this collection has more than 800 strains.
Stéphane Bach with KISSf team (B. Baratte, B. Josselin and T. Robert) will screen marine fungi extracts for bioactivity focused on disease-related protein kinases (involved notably in cancers and neurodegenerative disorders).
Remy Le Guével from ImPACcell will screen synergies and interaction modulation of active extracts / molecules on identified targets.
Identification of bioactive molecules will be performed by Arnaud Bondon from PRISM team, specialized in NMR analysis.
Maud Chetiveaux from Therrassay will provide an evaluation of therapeutic effect of molecules at the preclinical level.
ABiMS (Gildas Le Corguillé) provide bioinformatic support for MS and NMR data analysis with Workflow4Metabolomics.
THEY JOINED US
UMR1078 “Genetics, functional genomics and biotechnology” screen antibacterial activities against MDR clinical bacteria.